Migraine remedies often contain a drug to reduce nausea and vomiting (antiemetics), as well as a pain-killer. One problem in migraine, is that absorption from the stomach is much reduced once an attack starts, so that pain-killers taken by mouth have little effect. Anti-emetics can improve the absorption of the painkiller, so they are useful for migraines, even if nausea is not a symptom. The main drugs used are buclizine, cyclizine and metoclopramide. These are safe drugs with few side effects.
Because of the problem of non-absorption, it is very important to take migraine treatments as soon as an attack begins – or in advance, for those patients who have advance warning of their attacks, in the form of visual
disturbances, mood changes etc
Composition of migraine
preparations containing painkillers and other drugs
Midrid – paracetamol, plus a sedative, and a sympathomimetic
Migraleve – paracetamol, codeine and buclizine (anti-emetic) in the pink tablets; paracetamol and codeine in the yellow tablets.
Migravess – aspirin and metoclopramide
Paramax – paracetamol and metoclopramide (anti-emetic)
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